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1

Understanding the tumor immune microenvironment (TIME) for effective therapy

Binnewies, Mikhail, Roberts, Edward W., Kersten, Kelly, Chan, Vincent, Fearon, Douglas F., Merad, Miriam, Coussens, Lisa M., Gabrilovich, Dmitry I., Ostrand-Rosenberg, Suzanne, Hedrick, Catherine C.,

Journal:

Nature Medicine

Year:

2018

Language:

english

File:

PDF, 4.57 MB

english, 2018

2

Animal models of tumor immunity, immunotherapy and cancer vaccines

Suzanne Ostrand-Rosenberg

Journal:

Current Opinion in Immunology

Year:

2004

Language:

english

File:

PDF, 136 KB

english, 2004

3

Cancer and complement

Ostrand-Rosenberg, Suzanne

Journal:

Nature Biotechnology

Year:

2008

Language:

english

File:

PDF, 425 KB

english, 2008

4

Immune surveillance: a balance between protumor and antitumor immunity

Suzanne Ostrand-Rosenberg

Journal:

Current Opinion in Genetics & Development

Year:

2008

Language:

english

File:

PDF, 601 KB

english, 2008

5

Myeloid derived-suppressor cells: their role in cancer and obesity

Ostrand-Rosenberg, Suzanne

Journal:

Current Opinion in Immunology

Year:

2018

Language:

english

File:

PDF, 1.01 MB

english, 2018

6

Myeloid-Derived Suppressor Cells: Facilitators of Cancer and Obesity-Induced Cancer

Ostrand-Rosenberg, Suzanne

Journal:

Annual Review of Cancer Biology

Year:

2021

File:

PDF, 1.53 MB

2021

7

IL-1β regulates a novel myeloid-derived suppressor cell subset that impairs NK cell development and function

Moshe Elkabets, Vera S. G. Ribeiro, Charles A. Dinarello, Suzanne Ostrand-Rosenberg, James P. Di Santo, Ron N. Apte, Christian A. J. Vosshenrich

Journal:

European Journal of Immunology

Year:

2010

Language:

english

File:

PDF, 467 KB

english, 2010

8

MHC II lung cancer vaccines prime and boost tumor-specific CD4+ T cells that cross-react with multiple histologic subtypes of nonsmall cell lung cancer cells

Minu K. Srivastava, Jacobus J. Bosch, Ashley L. Wilson, Martin J. Edelman, Suzanne Ostrand-Rosenberg

Journal:

International Journal of Cancer

Year:

2010

Language:

english

File:

PDF, 923 KB

english, 2010

9

Tumor-specific immunity can be enhanced by transfection of tumor cells with syngeneic MHC-class-II genes or allogeneic MHC-class-I genes

S. Ostrand-Rosenberg, C. Roby, V. K. Clements, G. A. Cole

Journal:

International Journal of Cancer

Year:

1991

Language:

english

File:

PDF, 675 KB

english, 1991

10

Tumor immunotherapy: the tumor cell as an antigen-presenting cell

Suzanne Ostrand-Rosenberg

Journal:

Current Opinion in Immunology

Year:

1994

Language:

english

File:

PDF, 732 KB

english, 1994

11

MHC Class II Presentation of Endogenous Tumor Antigen by Cellular Vaccines Depends on the Endocytic Pathway but not H2-M

Ling Qi, Suzanne Ostrand-Rosenberg

Journal:

Year:

2000

Language:

english

File:

PDF, 416 KB

english, 2000

12

Resistance to 402AX teratocarcinoma involves immunity to minor histocompatibility antigens

Suzanne Ostrand-Rosenberg, Virginia Clements

Journal:

Year:

1987

Language:

english

File:

PDF, 540 KB

english, 1987

13

Resistance to murine 402ax teratocarcinoma: Regulation byH-21AandH-3toH-13region genes

Suzanne Ostrand-Rosenberg, Clare McCarthy

Journal:

Year:

1984

Language:

english

File:

PDF, 402 KB

english, 1984

14

Susceptibility of allogeneic mice to teratocarcinoma 402AX

Suzanne Ostrand-Rosenberg, Tami M. Rider, Alexandra Twarowski

Journal:

Year:

1980

Language:

english

File:

PDF, 402 KB

english, 1980

15

Expression ofHistocompatibility-2antigens on cultured cell lines derived from mouse blastocysts

Suzanne Ostrand-Rosenberg, Craig Hammerberg, Michael Edidin, Michael I. Sherman

Journal:

Year:

1977

Language:

english

File:

PDF, 599 KB

english, 1977

16

Topology of bovine red cell antigens as a function of the organization of their genes

Suzanne Ostrand-Rosenberg

Journal:

Year:

1976

Language:

english

File:

PDF, 1.70 MB

english, 1976

17

Introductory comments to Symposium in Writing: inhibitors of immunosurveillence and anti-tumor immunity

Suzanne Ostrand-Rosenberg

Journal:

Cancer Immunology, Immunotherapy

Year:

2004

Language:

english

File:

PDF, 102 KB

english, 2004

18

Signal transducer and activator of transcription 6 (Stat6) and CD1: inhibitors of immunosurveillance against primary tumors and metastatic disease

Suzanne Ostrand-Rosenberg, Pratima Sinha, Virginia Clements, SamudraI. Dissanayake, Seth Miller, Cordula Davis, Erika Danna

Journal:

Cancer Immunology, Immunotherapy

Year:

2004

Language:

english

File:

PDF, 192 KB

english, 2004

19

MHC class II and CD80 tumor cell–based vaccines are potent activators of type 1 CD4+T lymphocytes provided they do not coexpress invariant chain

Dan Ilkovitch, Suzanne Ostrand-Rosenberg

Journal:

Cancer Immunology, Immunotherapy

Year:

2004

Language:

english

File:

PDF, 338 KB

english, 2004

20

Tumor immunity: a balancing act between T cell activation, macrophage activation and tumor-induced immune suppression

Pratima Sinha, Virginia K. Clements, Seth Miller, Suzanne Ostrand-Rosenberg

Journal:

Cancer Immunology, Immunotherapy

Year:

2005

Language:

english

File:

PDF, 286 KB

english, 2005

21

The absence of invariant chain in MHC II cancer vaccines enhances the activation of tumor-reactive type 1 CD4+T lymphocytes

James A. Thompson, Minu K. Srivastava, Jacobus J. Bosch, Virginia K. Clements, Bruce R. Ksander, Suzanne Ostrand-Rosenberg

Journal:

Cancer Immunology, Immunotherapy

Year:

2008

Language:

english

File:

PDF, 553 KB

english, 2008

22

Lung cancer patients’ CD4+T cells are activated in vitro by MHC II cell-based vaccines despite the presence of myeloid-derived suppressor cells

Minu K. Srivastava, Jacobus J. Bosch, James A. Thompson, Bruce R. Ksander, Martin J. Edelman, Suzanne Ostrand-Rosenberg

Journal:

Cancer Immunology, Immunotherapy

Year:

2008

Language:

english

File:

PDF, 665 KB

english, 2008

23

Uveal melanoma cell-based vaccines express MHC II molecules that traffic via the endocytic and secretory pathways and activate CD8+cytotoxic, tumor-specific T cells

Jacobus J. Bosch, Uzoma K. Iheagwara, Sarah Reid, Minu K. Srivastava, Julie Wolf, Michal Lotem, Bruce R. Ksander, Suzanne Ostrand-Rosenberg

Journal:

Cancer Immunology, Immunotherapy

Year:

2010

Language:

english

File:

PDF, 584 KB

english, 2010

24

Alternative Ii-independent antigen-processing pathway in leukemic blasts involves TAP-dependent peptide loading of HLA class II complexes

Marvin M. van Luijn, Martine E. D. Chamuleau, Maaike E. Ressing, Emmanuel J. Wiertz, Suzanne Ostrand-Rosenberg, Yuri Souwer, Adri Zevenbergen, Gert J. Ossenkoppele, Arjan A. van de Loosdrecht, S. Mari

Journal:

Cancer Immunology, Immunotherapy

Year:

2010

Language:

english

File:

PDF, 658 KB

english, 2010

25

Myeloid-derived suppressor cells: more mechanisms for inhibiting antitumor immunity

Suzanne Ostrand-Rosenberg

Journal:

Cancer Immunology, Immunotherapy

Year:

2010

Language:

english

File:

PDF, 289 KB

english, 2010

26

Obituary: Joseph Lustgarten, 1963–2011

Suzanne Ostrand-Rosenberg, Esteban Celis, Peter Cohen, Zelig Eshher, Sandra Gendler, Dominique Hoelzinger, Lustgarten Lab Members, Arthur Hurwitz, Larry Pease, Linda Sherman

Journal:

Cancer Immunology, Immunotherapy

Year:

2011

Language:

english

File:

PDF, 117 KB

english, 2011

27

Immunotherapy with vaccines combining MHC class II/CD80+tumor cells with interleukin-12 reduces established metastatic disease and stimulates immune effectors and monokine induced by interferon γ

Beth A. Pulaski, Virginia K. Clements, Matthew R. Pipeling, Suzanne Ostrand-Rosenberg

Journal:

Cancer Immunology, Immunotherapy

Year:

2000

Language:

english

File:

PDF, 327 KB

english, 2000

28

Tumor antigen presentation: changing the rules

Todd D. Armstrong, Beth A. Pulaski, S. Ostrand-Rosenberg

Journal:

Cancer Immunology, Immunotherapy

Year:

1998

Language:

english

File:

PDF, 304 KB

english, 1998

29

Antagonism of the prostaglandin E receptor EP4 inhibits metastasis and enhances NK function

Namita Kundu, Xinrong Ma, Dawn Holt, Olga Goloubeva, Suzanne Ostrand-Rosenberg, Amy M. Fulton

Journal:

Breast Cancer Research and Treatment

Year:

2009

Language:

english

File:

PDF, 439 KB

english, 2009

30

Recognition of MHC TL Gene Products by γδ T Cells

Luc Van Kaer, Min Wu, Yoshiaki Ichikawa, Kouichi Ito, Marc Bonneville, Suzanne Ostrand-Rosenberg, Donal B. Murphy, Susumu Tonegawa

Journal:

Immunological Reviews

Year:

1991

Language:

english

File:

PDF, 8.51 MB

english, 1991

31

Cell-based vaccines for the stimulation of immunity to metastatic cancers

Suzanne Ostrand-Rosenberg, Beth A. Pulaski, Virginia K. Clements, Ling Qi, Matthew R. Pipeling, Laura A. Hanyok

Journal:

Immunological Reviews

Year:

1999

Language:

english

File:

PDF, 6.98 MB

english, 1999

32

Myeloid-Derived Suppressor Cells Inhibit T-Cell Activation by Depleting Cystine and Cysteine

Srivastava, M. K., Sinha, P., Clements, V. K., Rodriguez, P., Ostrand-Rosenberg, S.

Journal:

Cancer Research

Year:

2010

Language:

english

File:

PDF, 449 KB

english, 2010

33

MHC Class II-Transfected Tumor Cells Induce Long-Term Tumor-Specific Immunity in Autologous Mice

Sivasubramanian Baskar, Viola Azarenko, Elizabeth Garcia Marshall, Eric Hughes, Suzanne Ostrand-Rosenberg

Journal:

Cellular Immunology

Year:

1994

File:

PDF, 420 KB

1994

34

Teratocarcinoma cell MHC antigen expression is regulated in vitro by a soluble noninterferon factor

Suzanne Ostrand-Rosenberg, Mark L. Schwartzman, Toby T. Hecht, Lisa Marr

Journal:

Cellular Immunology

Year:

1986

Language:

english

File:

PDF, 570 KB

english, 1986

35

402AX teratocarcinoma MHC class I antigen expression is regulated in vivo by Lyt 1, Lyt 2, and L3t4 expressing splenic T cells

Suzanne Ostrand-Rosenberg, Virginia Clements, Lisa Mark

Journal:

Cellular Immunology

Year:

1986

Language:

english

File:

PDF, 682 KB

english, 1986

36

Transfection and expression of syngeneic H-2 genes does not reduce malignancy of H-2 negative teratocarcinoma cells in the autologous host

Suzanne Ostrand-Rosenberg, Geoffrey A. Cole, Michael I. Nishimura, Virginia K. Clements

Journal:

Cellular Immunology

Year:

1990

Language:

english

File:

PDF, 1.24 MB

english, 1990

37

Mouse hepa-1 tumor is rejected by H-2db-restricted CTL despite decreased MHC class I antigen expression

Michael I. Nishimura, Suzanne Ostrand-Rosenberg

Journal:

Cellular Immunology

Year:

1991

Language:

english

File:

PDF, 826 KB

english, 1991

38

Rejection of allogeneic tumor is not determined by host responses to MHC class I molecules and is mediated by CD4−CD8+ T lymphocytes that are not lytic for the tumor

Geoffrey A. Cole, Suzanne Ostrand-Rosenberg

Journal:

Cellular Immunology

Year:

1991

Language:

english

File:

PDF, 281 KB

english, 1991

39

Regulation of major histocompatibility gene expression in teratocarcinoma 402AX cells

S. Ostrand-Rosenberg, V. Clements, G. Cole, A. DeCloux, L. Marr, M. Schwartzman

Journal:

Cell Differentiation

Year:

1984

Language:

english

File:

PDF, 539 KB

english, 1984

40

Cross-talk between myeloid-derived suppressor cells (MDSC), macrophages, and dendritic cells enhances tumor-induced immune suppression

Ostrand-Rosenberg, Suzanne, Sinha, Pratima, Beury, Daniel W., Clements, Virginia K.

Journal:

Seminars in Cancer Biology

Year:

2012

Language:

english

File:

PDF, 744 KB

english, 2012

41

Gene dosage and antigenic expression on the cell surface of bovine erythrocytes

Suzanne Ostrand-Rosenberg

Journal:

Animal Blood Groups and Biochemical Genetics =Animal Genetics (Wiley)

Year:

1975

Language:

english

File:

PDF, 1.13 MB

english, 1975

42

Bovine leukocyte antigens

Suzanne Ostrand-Rosenberg, Clyde Stormont

Journal:

Animal Blood Groups and Biochemical Genetics =Animal Genetics (Wiley)

Year:

1974

Language:

english

File:

PDF, 363 KB

english, 1974

43

TRANSFECTION OF MAJOR HISTOCOMPATIBLITY COMPLEX CLASS I AND CLASS II GENES CAUSES TUMOUR REJECTION

S. Ostrand-Rosenberg, V. K. Clements, A. Thakur, G. A. Cole

Journal:

International Journal of Immunogenetics

Year:

1989

Language:

english

File:

PDF, 366 KB

english, 1989

44

Expression of MHC Class II and B7–1 and B7–2 costimulatory molecules accompanies tumor rejection and reduces the metastatic potential of tumor cells

S. Ostrand-Rosenberg, S. Baskar, N. Patterson, V. K. ClementsDepartment of Biological Sciences

Journal:

Tissue Antigens

Year:

1996

Language:

english

File:

PDF, 717 KB

english, 1996

45

Lack of Identity of the A Antigen and Concanavalin A Receptor on Bovine Erythrocytes; Implications for Membrane Structure

Suzanne Ostrand-Rosenberg

Journal:

Year:

1976

Language:

english

File:

PDF, 1013 KB

english, 1976

46

Tumor-induced myeloid-derived suppressor cell function is independent of IFN-γ and IL-4Rα

Pratima Sinha, Katherine H. Parker, Lucas Horn, Suzanne Ostrand-Rosenberg

Journal:

European Journal of Immunology

Year:

2012

Language:

english

File:

PDF, 1.17 MB

english, 2012

47

Cytoplasmic tail truncation of MHC class II molecules abrogates lipid raft-dependent signaling in a murine sarcoma

Stéphane Bécart, Niclas Setterblad, Suzanne Ostrand-Rosenberg, Dominique Charron, Nuala Mooney

Journal:

Human Immunology

Year:

2002

Language:

english

File:

PDF, 29 KB

english, 2002

48

Myeloid-Derived Suppressor Cells: Linking Inflammation and Cancer

Ostrand-Rosenberg, S., Sinha, P.

Journal:

The Journal of Immunology

Year:

2009

Language:

english

File:

PDF, 1.13 MB

english, 2009

49

Major Histocompatibility Complex Class II+ Invariant Chain Negative Breast Cancer Cells Present Unique Peptides that Activate Tumor-specific T Cells from Breast Cancer Patients

Chornoguz, O., Gapeev, A., O'Neill, M. C., Ostrand-Rosenberg, S.

Journal:

Molecular & Cellular Proteomics

Year:

2012

Language:

english

File:

PDF, 1.92 MB

english, 2012

50

Prostaglandin E2 Promotes Tumor Progression by Inducing Myeloid-Derived Suppressor Cells

Sinha, P., Clements, V. K., Fulton, A. M., Ostrand-Rosenberg, S.

Journal:

Cancer Research

Year:

2007

Language:

english

File:

PDF, 499 KB

english, 2007

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